Randomised Clinical Trial: Effect of AH Plus and Neosealer Flo on Postoperative Pain and Healing of Periapical Lesions

doi:10.3390/bioengineering12040376

★ Alto impactoQ1 · EngineeringImpact Factor · 4.791

AutoresJuan Algar, Cristian Docampo-Vázquez, Cristina Rico‐Romano, Ana Boquete‐Castro, C. Obispo, Juan Manuel Aragoneses

Por qué importa

Este ensayo clínico aleatorizado, publicado en Bioengineering, evalúa comparativamente el comportamiento postoperatorio y la cicatrización de lesiones periapicales tras el uso de dos cementos selladores endodónticos: AH Plus y el biocerámico Neosealer Flo. Se centró en la cuantificación del dolor postoperatorio mediante escala visual analógica y la evaluación de la calidad del sellado y la curación periapical a los seis meses, utilizando criterios de éxito de la AAE. Los hallazgos sugieren una ventaja del Neosealer Flo en la reducción del dolor a corto y medio plazo, si bien ambos materiales mostraron una eficacia similar en la curación periapical. Estos resultados son relevantes para la toma de decisiones clínicas en tratamientos de conductos, ofreciendo información sobre la posible mejora de la experiencia del paciente y la eficacia terapéutica de los selladores biocerámicos frente a los convencionales.

Abstract original

Apical periodontitis is a common inflammatory condition associated with root canal treatment (RCT) failure. The quality of the three-dimensional root canal seal is critical to the success of the treatment. Bioceramic sealants, such as Neosealer Flo, offer biological advantages such as osteoconduction, biocompatibility and sustained calcium ion release, which may improve apical healing. The aim of this study was to compare AH Plus and Neosealer Flo in terms of postoperative pain, extrusion and periapical healing. A single-blind, randomised clinical trial was conducted with 60 patients divided into AH Plus and Neosealer Flo groups. Post-operative pain was assessed using a visual analogue scale (VAS) at 24 and 48 h and at 7 days. Seal quality and periapical healing were assessed at 6 months using the AAE success criteria by clinical and radiographic evaluation. Neosealer Flo resulted in less postoperative pain at 24 h and 7 days compared to AH Plus. Extrusion did not significantly affect pain or correlate with the type of sealer used. Both materials achieved similar periapical healing rates. Neosealer Flo demonstrated advantages in pain reduction, while both sealants showed comparable efficacy.

Leer texto completo ↗DOI · 10.3390/bioengineering12040376

Autor Doctor&Cols

Ana Boquete Castro
Cirugía Oral e Implantología

Cómo citar

Algar J, Docampo-Vázquez C, Rico‐Romano C, Boquete‐Castro A, Obispo C, Aragoneses JM. Randomised Clinical Trial: Effect of AH Plus and Neosealer Flo on Postoperative Pain and Healing of Periapical Lesions. Bioengineering. 2025. doi:10.3390/bioengineering12040376