Preventive Antibiotic Therapy in Sinus Elevation Procedures: A Systematic Review

doi:10.11607/jomi.9930

Q3 · DentistryImpact Factor · 1.9

AutoresÁngel-Orión Salgado-Peralvo, Álvaro García-Sánchez, Naresh Kewalramani, Mario Romandini, Eugenio Velasco-Ortega

Por qué importa

Este artículo revisa sistemáticamente la evidencia disponible sobre la eficacia de la terapia antibiótica preventiva en cirugías de elevación de seno maxilar. El objetivo principal era determinar si el uso de antibióticos reduce las tasas de infección del injerto sinusal o de fracaso de implantes dentales, así como identificar el protocolo óptimo. La revisión incluyó estudios comparativos con un mínimo de 50 pacientes. Los resultados indican una escasez de evidencia concluyente. Únicamente un estudio retrospectivo no encontró diferencias significativas en el fracaso de implantes, pero no aportó datos sobre infecciones sinusales. Un ensayo clínico aleatorizado tampoco halló diferencias significativas en la tasa de infección sinusal entre diferentes pautas de administración antibiótica. Por lo tanto, no hay suficiente evidencia actual para respaldar el uso o la no utilización de antibióticos, ni para determinar la superioridad de un protocolo específico en estos procedimientos.

Abstract original

Purpose: To study whether the use of preventive antibiotic therapy reduces the sinus graft infection and/or dental implant failure rates in maxillary sinus elevation surgeries (primary outcome), and to identify the associated best protocol (secondary outcome). Materials and Methods: The MEDLINE (via PubMed), Web of Science, Scopus, LILACS, and OpenGrey databases were searched between December 2006 and December 2021. Prospective and retrospective comparative clinical studies with at least 50 patients and published in English were included. Animal studies, systematic reviews and meta-analyses, narrative literature reviews, books, case reports, letters to the editor, and commentaries were excluded. Assessment of the identified studies, data extraction, and risk of bias were performed independently by two reviewers. Authors were contacted if required. Collected data were reported by descriptive methods. Results: A total of 12 studies fulfilled the inclusion criteria. The only retrospective study comparing the use of antibiotics vs no use of them showed no statistically significant differences for implant failure; however, no data were reported for sinus infection rates. The only randomized clinical trial comparing different courses of antibiotics (only the day of surgery vs 7 additional postoperative days) reported no statistically significant differences between groups in terms of sinus infection rate. Conclusion: Not enough evidence is available to support either the use or nonuse of preventive antibiotic therapy for sinus elevation surgeries or to support the superiority of any protocol over others.

Leer texto completo ↗DOI · 10.11607/jomi.9930

Autores Doctor&Cols

Cómo citar

Salgado-Peralvo Á, García-Sánchez Á, Kewalramani N, Romandini M, Velasco-Ortega E. Preventive Antibiotic Therapy in Sinus Elevation Procedures: A Systematic Review. The International Journal of Oral & Maxillofacial Implants. 2023. doi:10.11607/jomi.9930