Povidone-Iodine as a Pre-Procedural Mouthwash to Reduce the Salivary Viral Load of SARS-CoV-2: A Systematic Review of Randomized Controlled Trials

doi:10.3390/ijerph19052877

★ Alto impactoQ1 · PsychologyImpact Factor · 3.251

AutoresAlvaro Garcia-Sanchez, Juan‐Francisco Peña‐Cardelles, Esther Ordonez-Fernandez, María Montero-Alonso, Naresh Kewalramani, Ángel-Orión Salgado-Peralvo, Dániel Végh, Angélica Gargano, Gabriela Parra, Lourdes-Isabela Guerra-Guajardo, Wataru Kozuma

Por qué importa

Se ha revisado la evidencia científica publicada en 2022 sobre el uso del enjuague bucal de povidona yodada (PVP-I) como medida pre-procedimiento para disminuir la carga viral de SARS-CoV-2 en saliva. El objetivo es evaluar si este tipo de enjuague puede reducir el riesgo de transmisión cruzada durante procedimientos clínicos y dentales. Tras analizar cuatro ensayos controlados aleatorizados, la revisión sistemática concluye que el PVP-I es efectivo contra el SARS-CoV-2 en saliva. Por lo tanto, su implementación antes de intervenciones podría ser una estrategia útil para minimizar la dispersión del virus en el ambiente sanitario, contribuyendo a la seguridad de pacientes y profesionales.

Abstract original

The use of pre-procedural rinses has been investigated to reduce the number of viral particles and bacteria in aerosols, potentially decreasing the risk of cross-infection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during medical and dental procedures. This review aims to confirm whether there is evidence in the literature describing a reduction in salivary load of SARS-CoV-2 when povidone-iodine (PVP-I) is used as a pre-intervention mouthwash. An search of the MEDLINE, Embase, SCOPUS, and the Cochrane library databases was conducted. The criteria used followed the PRISMA® Statement guidelines. Randomized controlled trials investigating the reduction of salivary load of SARS-CoV-2 using PVP-I were included. Ultimately, four articles were included that met the established criteria. According to the current evidence, PVP-I is effective against SARS-CoV-2 in saliva and could be implemented as a rinse before interventions to decrease the risk of cross-infection in healthcare settings.

Leer texto completo ↗DOI · 10.3390/ijerph19052877

Autores Doctor&Cols

Cómo citar

Garcia-Sanchez A, Peña‐Cardelles J, Ordonez-Fernandez E, Montero-Alonso M, Kewalramani N, Salgado-Peralvo Á, et al. Povidone-Iodine as a Pre-Procedural Mouthwash to Reduce the Salivary Viral Load of SARS-CoV-2: A Systematic Review of Randomized Controlled Trials. International Journal of Environmental Research and Public Health. 2022. doi:10.3390/ijerph19052877