Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: a case report solved with non-invasive treatment.

AutoresGerardo Gómez Moreno, M C Arribas-Fernández, Manuel Fernández Guerrero, Ana Boquete‐Castro, Antonio Aguilar‐Salvatierra, J Guardía, Daniele Botticelli, José Luís Calvo‐Guirado

Por qué importa

Se presenta el caso de una paciente de 75 años que desarrolló osteonecrosis de mandíbula dos años después de iniciar tratamiento con bifosfonatos intravenosos, un fármaco conocido por su potencial riesgo de inducir esta patología. El artículo describe su abordaje y resolución mediante un tratamiento no invasivo. La relevancia para el odontólogo radica en la identificación temprana de lesiones sospechosas de osteonecrosis en pacientes bajo terapia con bifosfonatos, dada la alta prevalencia y el impacto en la calidad de vida. Comprender la etiología y las opciones terapéuticas, incluso las no invasivas, es crucial para el manejo de estos casos complejos en la práctica diaria.

Abstract original

Bisphosphonates are a type of drugs known to inhibit bone resorption through complex interventions. Their primary mechanism of action is aimed at the cellular level, inhibiting osteoclast activity and, thus, bone resorption. Bisphosphonates are, therefore, very widely used, with many patients receiving continuous treatment for years. But it is well known that these drugs can produce osteonecrosis of the jaw and this is their principal risk. A 75-year-old woman received dental treatment before starting intravenous BP therapy for a breast cancer. She started intravenous bisphosphonate treatment with monthly protocol and after two years the patient presented a wound compatible with osteonecrosis of the jaw.

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Autor Doctor&Cols

Ana Boquete Castro
Cirugía Oral e Implantología

Cómo citar

Moreno GG, Arribas-Fernández MC, Guerrero MF, Boquete‐Castro A, Aguilar‐Salvatierra A, Guardía J, et al. Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: a case report solved with non-invasive treatment.. PubMed. 2014.