Disinfection Strategies for Implant-Related Prosthetic Materials: An In Vitro Evaluation of Citric Acid, Chlorhexidine and Polyethylene Glycol

doi:10.3390/dj14010008

★ Alto impactoQ1 · DentistryImpact Factor · 3.289

AutoresEduardo Escaf-Robles, Aritza Brizuela-Velasco, Daniel Robles, Saray Férnandez-Hernández, Javier Gil, Héctor De Llanos-Lanchares

Por qué importa

Este estudio in vitro evalúa la efectividad de distintas estrategias desinfectantes —ácido cítrico, clorhexidina y polietilenglicol— sobre materiales protésicos dentales empleados en implantología, frente a un control no tratado. Se analizaron tres materiales comunes (titanio grado V, zirconio con cerámica y PMMA) y tres bacterias relevantes en patología oral. La clorhexidina mostró mayor poder inhibitorio a corto plazo (tres días), mientras que el ácido cítrico y el polietilenglicol demostraron una eficacia superior tras 21 días de incubación. El ácido cítrico, además, exhibió efectos diferenciales sobre el titanio grado V. Estos hallazgos son relevantes para la elección de protocolos de desinfección de componentes protésicos, tanto en el laboratorio como potencialmente en la clínica, con implicaciones para la prevención de infecciones asociadas a implantes.

Abstract original

Background/Objectives: There is evidence of possible contamination of prosthetic components originating from dental laboratories. The aim of this study is to investigate the disinfectant effect of citric acid and polyethylene glycol on implant-prosthetic materials in comparison with an untreated control and chlorhexidine. Methods: A total of 720 disks made of three different materials (titanium grade V, zirconia coated with feldspathic ceramic, and PMMA) contaminated with three bacteria (Staphylococcus aureus, Enterococcus faecalis, and porphyromonas gingivalis) were analyzed. Four treatment groups were tested: citric acid, polyethylene glycol, chlorhexidine and an untreated control group. Two assessment periods (3 and 21 days of incubation) were used, with bacterial metabolic activity measured using the resazurin reduction test and then analyzed by electron microscopy. Results: The results show that chlorhexidine has a superior inhibitory effect on all materials and bacterial strains in the short-term evaluation (3 days), while citric acid and polyethylene glycol showed higher efficacy after 21 days. Citric acid also exhibits differential effects when applied to grade V titanium. These differences were statistically significant at p < 0.05. Conclusions: There is evidence to recommend chlorhexidine for the disinfection of laboratory prosthetic components, but the enhanced effect of citric acid on grade V titanium and its long-term efficacy make it clinically promising candidate.

Leer texto completo ↗DOI · 10.3390/dj14010008

Autor Doctor&Cols

Daniel Robles Cantero
Cirugía Oral e Implantología

Cómo citar

Escaf-Robles E, Brizuela-Velasco A, Robles D, Férnandez-Hernández S, Gil J, Llanos-Lanchares HD. Disinfection Strategies for Implant-Related Prosthetic Materials: An In Vitro Evaluation of Citric Acid, Chlorhexidine and Polyethylene Glycol. Dentistry Journal. 2025. doi:10.3390/dj14010008