AutoresAntonio Juan Flichy‐Fernández, Miguel Padial‐Molina, Natividad Martín‐Morales, T. Alegre‐Domingo, Miguel Peñarrocha Diago, Francisco O’Valle, Pablo Galindo‐Moreno
Este estudio comparó el comportamiento de dos biomateriales de injerto óseo comúnmente utilizados en elevaciones de seno maxilar: hueso bovino inorgánico y fosfato de calcio bifásico. Se evaluaron 68 sitios implantarios en 42 pacientes mediante análisis histológico y morfométrico de las muestras óseas obtenidas durante la colocación de implantes. Los resultados indican que ambos materiales generan una cantidad similar de tejido mineralizado y de hueso injertado. Sin embargo, se observaron diferencias en la composición tisular: el fosfato de calcio bifásico se asoció con una mayor proporción de tejido conectivo cicatricial y una menor cantidad de material remanente. Ninguno de los implantes presentó complicaciones un año después del procedimiento. Estos hallazgos son relevantes para la selección del biomaterial más adecuado según las características histopatológicas deseadas en la regeneración ósea para la posterior colocación de implantes dentales.
Background: To compare the histological and histomorphometrical outcomes after sinus floor elevation using an anorganic bovine bone biomaterial or a biphasic calcium phosphate biomaterial. Material and Methods: Patients who needed maxillary sinus elevation were included in this study. A total of 68 implant sites were evaluated from a total of 42 patients. Twenty patients were treated with anorganic bovine bone, while 22 were treated with biphasic calcium phosphate biomaterial. Morphological and morphometrical studies were performed on the bone samples collected during implant placement. Results: Both biomaterials induced similar relative areas of mineralized tissue overall, particularly if only the area of grafted bone was considered. In turn, a higher proportion of non-mineralized tissue was observed in cases of biphasic calcium phosphate biomaterial with less area of remnant biomaterial particles. None of the implants failed at one year of follow-up. Conclusions: Although both biomaterials induce a similar amount of bone formation, the histopathological characteristics of the grafts are different, with a greater proportion of scar connective tissue with the biphasic calcium phosphate biomaterial.
Flichy‐Fernández AJ, Padial‐Molina M, Martín‐Morales N, Alegre‐Domingo T, Diago MP, O’Valle F, et al. Anorganic Bovine Bone vs. Biphasic Calcium Phosphate in a Large Series of Maxillary Sinus Floor Elevations—A Non-Randomized Clinico-Morphological Study. Journal of Clinical Medicine. 2025. doi:10.3390/jcm14238464
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